Metabolism of Phosphatidylglycerol and Lysyl Phosphatidylglycerol in Staphylococcus aureus
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چکیده
منابع مشابه
Metabolism of Phosphatidylglycerol and Lysyl Phosphatidylglycerol in Staphylococcus aureus.
The metabolism of phosphatidylglycerol and lysyl phosphatidylglycerol was studied in Staphylococcus aureus under four conditions: growing at pH 7.0 and 5.2, and not growing (resting) at pH 7.0 and 5.2. Measurements of the amounts of phosphatidylglycerol and lysyl phosphatidylglycerol, as well as labeling and pulsechase experiments, revealed that the phosphate group of the former and the lysyl g...
متن کاملMetabolism of phosphatidylglycerol, lysylphosphatidylglycerol, and cardiolipin of Staphylococcus aureus.
Staphylococcus aureus accumulated cardiolipin (CL) and lost phosphatidylglycerol (PG) during the stationary phase of growth. The minor lipids, phosphatidylethanolamine and phosphatidylglucose, also accumulated, whereas the lysylphosphatidylglycerol (LPG) content of the membrane remained constant as stationary phase continued. During exponential growth, the proportions and total content of phosp...
متن کاملBiosynthesis of cardiolipin from phosphatidylglycerol in Staphylococcus aureus.
Cardiolipin (CL) synthetase from Staphylococcus aureus catalyzes the complete conversion of two molecules of phosphatidylglycerol (PG) to one molecule of CL and one molecule of glycerol. The fatty acids and phosphates of the two PG molecules can be quantitatively recovered in the CL. The enzyme is membrane-bound, shows a linear relationship with the product formed between 10 and 125 mug of memb...
متن کاملCharacterization of the Staphylococcus aureus mprF gene, involved in lysinylation of phosphatidylglycerol.
Lysylphosphatidylglycerol (LPG) is a basic phospholipid in which L-lysine from lysyl-tRNA is transferred to phosphatidylglycerol (PG). This study examined whether the Staphylococcus aureus mprF gene encodes LPG synthetase. A crude membrane fraction prepared from wild-type S. aureus cells had LPG synthetase activity that depended on PG and lysyl-tRNA, whereas the membrane fraction from an mprF d...
متن کاملThe biosynthesis of phosphatidylglycerol.
Phosphatidylglycerol has been shown to be a constituent of the lipids of both plant and animal tissues by Benson and Maruo (1) and Strickland and Benson (2). It has also been detected in bacteria (3,4). Benson and Maruo (1) have called attention to the rapid rate of metabolism of phosphatidylglycerol in plants, and Kanfer and Kennedy 1 have obtained evidence that this phosphatide is a metabolic...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1970
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.104.3.1135-1144.1970